Production of new type of electrochemical drug sensors for cardiovascular diseases

Iranian scientists announced earlier this year that they have successfully synthesized and evaluated a new type of electrochemical sensors to measure verapamil cardiovascular drug. Magnetic nanoparticles and acidic functionalized silicate mesoporous were used to produce a sensor able to detect low concentrations of verapamil. This research was carried out in a few stages. The synthesis of magnetic nanoparticles and functionalized silicate mesoporous particles was among the very first steps which were carried out in Iran Pasteur Institute. After the synthesis stage, the researchers doped magnetic nanoparticles inside the silicate mesoporous particles functionalized with acidic groups. After carrying out surface studying tests, they produced the desired composite and used it in the production of electrochemical nanosensor based on the technology to produce carbon paste sensors. Then, the produced sensor was tested and evaluated in various experiments by using standard and biological samples. At the end, the oxidation mechanism and the obtained products were proposed based on electrochemical techniques. Results of the research have been published on 1 February 2013 in Electrochimica Acta, vol. 89. For more information about the details of the research, study the full article on pages 660-668 on the same journal.